CKAP2L

Across TCGA cell cohorts, CKAP2L mutation is significantly associated with the RNA expression of many other genes, with 25 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible CKAP2L-associated genes across cancer lineages are OR10K2, OR10T2, and C1QTNF7. Each is linked with CKAP2L in more than 1 cancer types. Because this analysis shows association rather than direction, both CKAP2L-to-partner and partner-to-CKAP2L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10K2 grouped by CKAP2L-low versus CKAP2L-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CKAP2L→partner) and Y-score (partner→CKAP2L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	OR10K2 →	+0.047	+4.781	<.001	.003	3	1
BREAST	OR10T2 →	+0.137	+4.781	<.001	.003	3	1
LARGE_INTESTINE	C1QTNF7 →	+0.098	+4.108	<.001	.008	3	1
LARGE_INTESTINE	DEFA4 →	+0.032	+4.437	<.001	.004	3	1
LARGE_INTESTINE	TBC1D21 →	+0.012	+4.437	<.001	.004	3	1
LARGE_INTESTINE	ACER1 →	+0.098	+3.823	.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

OR10K2 by CKAP2L expression — BREAST

Explore this box plot interactively →