CKAP2

Across TCGA patient cohorts, CKAP2 protein abundance is significantly associated with the protein abundance of many other proteins, with 30,131 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CKAP2-associated proteins across cancer lineages are RRM2, TOP2A, and TPX2. Each is linked with CKAP2 in more than 9 cancer types. Because this analysis shows association rather than direction, both CKAP2-to-partner and partner-to-CKAP2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CKAP2 versus RRM2 in LUAD, with a Pearson correlation of 0.73.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CKAP2→partner) and Y-score (partner→CKAP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RRM2 →	+1.034	+0.858	<.001	<.001	3	10
LUAD	TOP2A →	+1.292	+1.019	<.001	<.001	3	10
LUAD	TPX2 →	+1.108	+1.076	<.001	<.001	3	10
COAD	OBI1_S210 →	+1.173	+1.072	<.001	<.001	3	10
LUAD	ATAD2_S342 →	+1.943	+0.976	<.001	<.001	3	9
LUAD	CDK1 →	+1.189	+1.078	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 30,131 associations by consensus.

CKAP2 vs RRM2 — LUAD

Explore this scatter interactively →