CIZ1

Across TCGA cell cohorts, CIZ1 mutation is significantly associated with the RNA expression of many other genes, with 513 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CIZ1-associated genes across cancer lineages are OR13D1, C16orf90, and OR4E2. Each is linked with CIZ1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CIZ1-to-partner and partner-to-CIZ1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR13D1 grouped by CIZ1-low versus CIZ1-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CIZ1→partner) and Y-score (partner→CIZ1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	OR13D1 →	+0.026	+4.217	<.001	.005	3	1
URINARY_TRACT	C16orf90 →	+0.017	+4.087	<.001	.009	3	1
BREAST	OR4E2 →	+0.025	+5.169	<.001	.005	3	1
LUNG_NSCLC_LUAD	AMELX →	+0.076	+4.887	<.001	.009	3	1
LUNG_NSCLC_LUAD	GNG8 →	+0.327	+4.887	<.001	.009	3	1
LUNG_NSCLC_LUAD	OR4A47 →	+0.029	+5.228	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 513 associations by consensus.

OR13D1 by CIZ1 expression — URINARY_TRACT

Explore this box plot interactively →