CISTR

Across TCGA patient cohorts, CISTR RNA expression is significantly associated with the protein abundance of many other proteins, with 8,415 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CISTR-associated proteins across cancer lineages are ITPKC, SAFB, and SIK3_S626. Each is linked with CISTR in more than 2 cancer types. Because this analysis shows association rather than direction, both CISTR-to-partner and partner-to-CISTR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CISTR versus ITPKC in GBM, with a Pearson correlation of -0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CISTR→partner) and Y-score (partner→CISTR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ITPKC →	-0.421	-0.288	<.001	<.001	3	3
GBM	SAFB →	+0.196	+0.207	.002	.002	3	3
PDAC	SIK3_S626 →	-1.080	-0.024	<.001	<.001	3	2
UCEC	XKR4_T211 →	+1.607	+0.566	.002	.005	3	2
PDAC	RALGPS2_T326 →	-0.255	-0.026	.008	.009	3	2
GBM	CRYBG3_S941 →	-0.525	-0.340	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,415 associations by consensus.

CISTR vs ITPKC — GBM

Explore this scatter interactively →