CISD3

Across TCGA patient cohorts, CISD3 protein abundance is significantly associated with the RNA expression of many other genes, with 6,693 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CISD3-associated genes across cancer lineages are SERPINA5, TTC22, and AGPAT4. Each is linked with CISD3 in more than 3 cancer types. Because this analysis shows association rather than direction, both CISD3-to-partner and partner-to-CISD3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CISD3 versus SERPINA5 in UCEC, with a Pearson correlation of -0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CISD3→partner) and Y-score (partner→CISD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SERPINA5 →	-1.244	-0.314	.008	.001	3	4
LSCC	TTC22 →	+0.705	+0.224	<.001	.005	3	4
BRCA	AGPAT4 →	-0.699	-0.857	<.001	<.001	3	4
UCEC	GAPDH →	-1.354	-0.387	<.001	.009	3	3
UCEC	RBMX2 →	-0.468	-0.276	.003	.006	3	3
BRCA	GPR160 →	+1.188	+0.552	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,693 associations by consensus.

CISD3 vs SERPINA5 — UCEC

Explore this scatter interactively →