CIRBP-AS1

Across TCGA pan-cancer cohorts, CIRBP-AS1 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated CIRBP-AS1 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher CIRBP-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated CIRBP-AS1 expression acts as an unfavorable survival marker, although some lineages such as PAAD and LUSC show a favorable association.

ACC, PAAD, and LGG are the cancer types where CIRBP-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Tertile	All	0.372	0.769	<.001	98	view →
PAAD	OS	Median	All	0.482	0.238	.002	59	view →
LGG	DFS	Median	All	0.643	0.832	<.001	54	view →
LUAD	DFS	Tertile	All	0.770	0.852	.005	32	view →
KIRC	DFS	Quartile	II,III,IV	0.391	0.629	.004	27	view →
UVM	DFS	Quartile	III,IV	0.229	0.650	.008	25	view →
UCS	OS	Median	IV	0.302	0.817	.002	24	view →
DLBC	DFS	Median	All	0.607	0.912	.008	22	view →
KIRP	DFS	Tertile	III,IV	0.131	0.619	.012	21	view →
LIHC	DFS	Median	All	0.469	0.632	.001	20	view →
COAD	OS	Median	All	0.814	0.919	.003	19	view →
KICH	DFS	Median	All	0.763	1.000	.023	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

CIRBP-AS1–ACC (DFS)

Open the ACC breakdown →