CIRBP-AS1

Across TCGA pan-cancer cohorts, CIRBP-AS1 RNA differs between tumor and matched normal tissue in 17 of 18 cancer types tested, making tumor–normal expression one of CIRBP-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where CIRBP-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types CIRBP-AS1 is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.

THCA, KIRC, and LIHC are the cancer types where CIRBP-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CIRBP-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Male	III,IV	−1.171	<.001	11	view →
KIRC	Male	IV	+0.529	<.001	11	view →
LIHC	All	II,III,IV	+0.661	<.001	7	view →
COAD	All	II,III,IV	+0.478	<.001	7	view →
BLCA	All	All	+0.772	.001	6	view →
BRCA	All	All	+0.263	<.001	6	view →
LUSC	All	All	+0.639	<.001	5	view →
STAD	All	II,III,IV	+0.585	<.001	5	view →
UCEC	All	All	+0.619	.001	4	view →
KIRP	All	IV	+0.897	.019	3	view →
LUAD	Female	All	+0.312	.024	3	view →
CHOL	All	All	+1.180	<.001	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 17 lineages.

CIRBP-AS1–THCA

Open the THCA breakdown →