Across TCGA patient cohorts, CIPC mutation is significantly associated with the RNA expression of many other genes, with 686 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CIPC-associated genes across cancer lineages are RNU1-57P, RNA5SP405, and RNA5SP359. Each is linked with CIPC in more than 1 cancer types. Because this analysis shows association rather than direction, both CIPC-to-partner and partner-to-CIPC results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CIPC→partner) and Y-score (partner→CIPC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	RNU1-57P →	+0.631	+5.026	<.001	.009	3	2
UCEC	RNA5SP405 →	+0.350	+3.675	<.001	<.001	3	2
UCEC	RNA5SP359 →	+0.361	+2.152	<.001	.009	3	2
UCEC	SNORA36A →	+0.441	+2.146	.004	.001	3	2
UCEC	IGHV3-20 →	+1.321	+2.708	.002	.003	3	2
UCEC	MTHFD2P5 →	+0.123	+2.069	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 686 associations by consensus.

Exploration

CIPC survival (RNA) · tumor vs normal (RNA) · all CIPC data types