CINP

Across TCGA patient cohorts, CINP protein abundance is significantly associated with the RNA expression of many other genes, with 7,727 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible CINP-associated genes across cancer lineages are SPATA5, SPATA5L1, and HTRA2. Each is linked with CINP in more than 4 cancer types. Because this analysis shows association rather than direction, both CINP-to-partner and partner-to-CINP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CINP versus SPATA5 in LSCC, with a Pearson correlation of 0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CINP→partner) and Y-score (partner→CINP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SPATA5 →	+0.542	+0.297	<.001	<.001	3	5
BRCA	SPATA5L1 →	+0.599	+0.303	<.001	<.001	2	5
LSCC	HTRA2 →	+0.411	+0.225	<.001	.001	3	3
OV	GAMT →	+0.864	+0.326	.006	.005	3	3
BRCA	NUDT6 →	+0.440	+0.218	<.001	<.001	3	3
COAD	KLHL3 →	-1.125	-0.524	.002	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,727 associations by consensus.

CINP vs SPATA5 — LSCC

Explore this scatter interactively →