CICP4

Across TCGA patient cohorts, CICP4 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,633 significant associations in total. STAD shows the largest number of these associations.

The most reproducible CICP4-associated GO terms across cancer lineages are Regulation of RNA splicing, Nucleotide-excision repair, and Maintenance of cell number. Each is linked with CICP4 in more than 24 cancer types. Because this analysis shows association rather than direction, both CICP4-to-partner and partner-to-CICP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of RNA splicing grouped by CICP4-low versus CICP4-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CICP4→partner) and Y-score (partner→CICP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of RNA splicing →	+0.069	+0.052	<.001	<.001	3	25
DLBC	Nucleotide-excision repair →	+0.057	+0.045	<.001	.002	3	25
STAD	Maintenance of cell number →	+0.058	+0.057	<.001	<.001	3	25
ESCA	Nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay →	+0.078	+0.072	<.001	<.001	3	24
STAD	Protein acylation →	+0.064	+0.056	<.001	<.001	3	24
STAD	Regulation of DNA repair →	+0.061	+0.056	<.001	<.001	3	24

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,633 associations by consensus.

Regulation of RNA splicing by CICP4 expression — STAD

Explore this box plot interactively →