CICP4

Across TCGA pan-cancer cohorts, CICP4 RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated CICP4 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher CICP4 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated CICP4 expression acts as an unfavorable survival marker, although some lineages such as STAD and LUAD show a favorable association.

MESO, OV, and COAD are the cancer types where CICP4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Tertile	IV	0.077	0.592	.019	45	view →
OV	OS	Tertile	III,IV	0.247	0.370	.003	34	view →
COAD	DFS	Tertile	All	0.474	0.719	<.001	33	view →
LIHC	DFS	Tertile	II,III,IV	0.208	0.453	.001	30	view →
UCEC	OS	Tertile	All	0.313	0.710	.007	24	view →
UCS	OS	Tertile	All	0.225	0.607	.028	18	view →
ACC	OS	Tertile	IV	0.251	0.776	.009	18	view →
ESCA	DFS	Median	IV	0.213	0.626	.026	12	view →
DLBC	OS	Tertile	All	0.641	0.953	.043	9	view →
UVM	DFS	Tertile	III,IV	0.129	0.673	.017	9	view →
STAD	OS	Tertile	IV	0.773	0.309	.014	6	view →
PCPG	OS	Quartile	All	0.763	1.000	.006	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

CICP4–MESO (OS)

Open the MESO breakdown →