CICP21

Across TCGA pan-cancer cohorts, CICP21 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of CICP21’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where CICP21 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CICP21 is over-expressed in tumor.

HNSC, KIRP, and KIRC are the cancer types where CICP21 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CICP21 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	III,IV	+0.013	.036	3	view →
KIRP	All	All	+0.015	.020	2	view →
KIRC	Male	All	+0.007	.023	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

CICP21–HNSC

Open the HNSC breakdown →