CIBAR1P2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CIBAR1P2 mutation is significantly associated with the RNA expression of many other genes, with 746 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CIBAR1P2-associated genes across cancer lineages are TRAJ57, NRBF2P3, and RN7SL643P. Each is linked with CIBAR1P2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CIBAR1P2-to-partner and partner-to-CIBAR1P2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRAJ57 grouped by CIBAR1P2-low versus CIBAR1P2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CIBAR1P2→partner) and Y-score (partner→CIBAR1P2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECTRAJ57 →+0.389+2.096<.001.00632
UCECNRBF2P3 →+0.097+1.785.002.00632
SKCMRN7SL643P →+0.085+4.993<.001.00232
COADRN7SL424P →+0.221+4.547.007.00532
SKCMMIR2278 →+0.333+3.869<.001.00432
SKCMRNU6-577P →+0.522+3.796<.001.00232
Each partner links to its Q-omics profile. Showing the 6 strongest of 746 associations by consensus.

TRAJ57 by CIBAR1P2 expression — UCEC

Box plot of TRAJ57 in CIBAR1P2-low vs CIBAR1P2-high samples in UCEC.

Explore this box plot interactively →

Exploration