CIB3

Across TCGA patient cohorts, CIB3 mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible CIB3-associated genes across cancer lineages are Erythrocytes, MPP, and CD4+ T-cells. Each is linked with CIB3 in more than 1 cancer types. Because this analysis shows association rather than direction, both CIB3-to-partner and partner-to-CIB3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Erythrocytes grouped by CIB3-low versus CIB3-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CIB3→partner) and Y-score (partner→CIB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Erythrocytes →	+0.021	+2.917	.031	.030	3	2
SKCM	MPP →	+0.014	+1.996	.033	.016	3	1
LUAD	CD4+ T-cells →	+0.021	+6.345	<.001	.016	3	1
SKCM	DC →	-0.021	-2.290	.046	.036	2	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Erythrocytes by CIB3 expression — SKCM

Explore this box plot interactively →