CIB3

Across TCGA cell cohorts, CIB3 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,359 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible CIB3-associated GO terms across cancer lineages are Lipid droplet formation, Cellular response to interleukin-6, and Response to muramyl dipeptide. Each is linked with CIB3 in more than 4 cancer types. Because this analysis shows association rather than direction, both CIB3-to-partner and partner-to-CIB3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Lipid droplet formation grouped by CIB3-low versus CIB3-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CIB3→partner) and Y-score (partner→CIB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Lipid droplet formation →	+0.067	+0.305	.001	.002	3	5
BREAST	Cellular response to interleukin-6 →	-0.062	-0.643	.008	.001	3	5
BREAST	Response to muramyl dipeptide →	-0.148	-0.878	<.001	<.001	3	5
LUNG_NSCLC_LUAD	Morula formation →	+1.020	+0.270	<.001	.001	3	4
LUNG_NSCLC_LUAD	Protein targeting to Golgi apparatus →	+0.123	+0.332	<.001	.002	3	4
LUNG_NSCLC_LUAD	Regulation of late endosome to lysosome transport →	+0.103	+0.181	<.001	.008	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,359 associations by consensus.

Lipid droplet formation by CIB3 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →