CIART

Across TCGA cell cohorts, CIART RNA expression is significantly associated with the go_rna of many other GO terms, with 2,661 significant associations in total. CNS shows the largest number of these associations.

The most reproducible CIART-associated GO terms across cancer lineages are Response to X-ray, Macroautophagy, and Autophagy of mitochondrion. Each is linked with CIART in more than 5 cancer types. Because this analysis shows association rather than direction, both CIART-to-partner and partner-to-CIART results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to X-ray grouped by CIART-low versus CIART-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CIART→partner) and Y-score (partner→CIART) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Response to X-ray →	-0.100	-1.800	.002	.005	3	6
LUNG_NSCLC_LUAD	Macroautophagy →	+0.039	+1.418	.002	.008	3	6
LUNG_NSCLC_LUAD	Autophagy of mitochondrion →	+0.041	+1.208	.004	.007	3	6
PANCREAS	Regulation of autophagy of mitochondrion →	+0.055	+1.060	.001	.001	3	6
BREAST	Ubiquinone metabolic process →	-0.093	-1.822	<.001	<.001	3	6
LUNG_SCLC	Protein polyubiquitination →	+0.032	+1.136	.004	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,661 associations by consensus.

Response to X-ray by CIART expression — LUNG_NSCLC_LUSC

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