CHURC1

Across TCGA patient cohorts, CHURC1 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,524 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CHURC1-associated proteins across cancer lineages are RPL7, PPM1A, and RPL14. Each is linked with CHURC1 in more than 6 cancer types. Because this analysis shows association rather than direction, both CHURC1-to-partner and partner-to-CHURC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHURC1 versus RPL7 in GBM, with a Pearson correlation of -0.30.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CHURC1→partner) and Y-score (partner→CHURC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RPL7 →	-0.431	-0.303	<.001	<.001	2	7
LUAD	PPM1A →	+0.187	+0.499	.001	<.001	3	5
GBM	RPL14 →	-0.464	-0.375	<.001	<.001	3	5
CCRCC	RPL21 →	-0.266	-0.390	.001	.001	3	5
BRCA	RPL4 →	-0.364	-0.674	<.001	<.001	3	5
BRCA	RPS9 →	-0.276	-0.518	.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,524 associations by consensus.

CHURC1 vs RPL7 — GBM

Explore this scatter interactively →