CHTF18

Across TCGA cell cohorts, CHTF18 mutation is significantly associated with the RNA expression of many other genes, with 244 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CHTF18-associated genes across cancer lineages are CCDC60, FHL5, and GJA10. Each is linked with CHTF18 in more than 1 cancer types. Because this analysis shows association rather than direction, both CHTF18-to-partner and partner-to-CHTF18 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCDC60 grouped by CHTF18-low versus CHTF18-high in BLOOD_Myeloma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHTF18→partner) and Y-score (partner→CHTF18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	CCDC60 →	+0.033	+4.807	<.001	.006	3	2
BREAST	FHL5 →	+0.053	+3.727	.001	.002	3	2
BLOOD_Myeloma	GJA10 →	+0.023	+4.807	<.001	.006	3	1
BLOOD_Myeloma	EVX2 →	+0.016	+4.807	<.001	.006	3	1
BLOOD_Myeloma	FAM47B →	+0.006	+4.807	<.001	.006	3	1
BLOOD_Myeloma	FSCB →	+0.006	+4.807	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 244 associations by consensus.

CCDC60 by CHTF18 expression — BLOOD_Myeloma

Explore this box plot interactively →