CHSY1

Across TCGA cell cohorts, CHSY1 mutation is significantly associated with the RNA expression of many other genes, with 16 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CHSY1-associated genes across cancer lineages are S100G, CCR8, and C9orf92. Each is linked with CHSY1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CHSY1-to-partner and partner-to-CHSY1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, S100G grouped by CHSY1-low versus CHSY1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHSY1→partner) and Y-score (partner→CHSY1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	S100G →	+1.166	+3.103	<.001	.004	3	2
SOFT_TISSUE	CCR8 →	+0.016	+4.369	<.001	.008	3	1
SOFT_TISSUE	C9orf92 →	+0.144	+4.369	<.001	.008	3	1
SOFT_TISSUE	SERPINB11 →	+0.831	+4.222	<.001	.007	3	1
SOFT_TISSUE	GSG1L2 →	+0.299	+4.369	<.001	.008	3	1
BLOOD_Leukemia	KSR2 →	+0.413	+3.798	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

S100G by CHSY1 expression — LARGE_INTESTINE

Explore this box plot interactively →