CHST6

Across TCGA patient cohorts, CHST6 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,288 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CHST6-associated proteins across cancer lineages are ZFYVE19, MLLT6_S258, and SART3. Each is linked with CHST6 in more than 5 cancer types. Because this analysis shows association rather than direction, both CHST6-to-partner and partner-to-CHST6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHST6 versus ZFYVE19 in PDAC, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CHST6→partner) and Y-score (partner→CHST6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	ZFYVE19 →	+0.339	+1.063	<.001	<.001	3	6
BRCA	MLLT6_S258 →	-0.597	-0.707	<.001	<.001	3	6
GBM	SART3 →	-0.232	-0.664	<.001	.005	3	5
UCEC	SLPI →	+1.488	+1.484	<.001	<.001	3	5
GBM	UPP1 →	+0.840	+0.907	<.001	.001	3	5
GBM	S100A11 →	+0.831	+1.068	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,288 associations by consensus.

CHST6 vs ZFYVE19 — PDAC

Explore this scatter interactively →