CHST6

Across TCGA patient cohorts, CHST6 mutation is significantly associated with the RNA expression of many other genes, with 1,794 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CHST6-associated genes across cancer lineages are ERI1, LINC01607, and KIR2DL4. Each is linked with CHST6 in more than 2 cancer types. Because this analysis shows association rather than direction, both CHST6-to-partner and partner-to-CHST6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ERI1 grouped by CHST6-low versus CHST6-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHST6→partner) and Y-score (partner→CHST6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ERI1 →	+0.602	+1.736	<.001	.007	3	3
UCEC	LINC01607 →	-0.717	-2.885	<.001	.001	3	3
UCEC	KIR2DL4 →	+0.994	+2.502	<.001	<.001	3	3
UCEC	TRGC2 →	+0.873	+3.721	<.001	<.001	3	3
BLCA	MTCO2P31 →	+0.050	+4.685	<.001	.007	3	2
BLCA	H3P22 →	+0.090	+4.685	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,794 associations by consensus.

ERI1 by CHST6 expression — UCEC

Explore this box plot interactively →