CHST12

Across TCGA cell cohorts, CHST12 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,057 significant associations in total. CNS shows the largest number of these associations.

The most reproducible CHST12-associated GO terms across cancer lineages are Multi-pass transmembrane protein insertion into ER membrane, Protein-containing complex disassembly, and Dermatan sulfate proteoglycan metabolic process. Each is linked with CHST12 in more than 15 cancer types. Because this analysis shows association rather than direction, both CHST12-to-partner and partner-to-CHST12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Multi-pass transmembrane protein insertion into ER membrane grouped by CHST12-low versus CHST12-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CHST12→partner) and Y-score (partner→CHST12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Multi-pass transmembrane protein insertion into ER membrane →	+0.131	+1.335	<.001	.001	3	16
UPPER_AERODIGESTIVE_TRACT	Protein-containing complex disassembly →	+0.095	+1.389	<.001	<.001	3	15
OESOPHAGUS	Dermatan sulfate proteoglycan metabolic process →	+0.134	+1.887	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Regulation of pattern recognition receptor signaling pathway →	+0.074	+1.513	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Regulation of cytoplasmic pattern recognition receptor signaling pathway →	+0.062	+1.280	.002	.001	3	15
LUNG_NSCLC_LUSC	Actin filament depolymerization →	+0.254	+1.339	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,057 associations by consensus.

Multi-pass transmembrane protein insertion into ER membrane by CHST12 expression — BLOOD_Lymphoma

Explore this box plot interactively →