CHST12

Across TCGA cell cohorts, CHST12 mutation is significantly associated with the RNA expression of many other genes, with 133 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CHST12-associated genes across cancer lineages are UNC45B, C20orf85, and SLCO1B1. Each is linked with CHST12 in more than 1 cancer types. Because this analysis shows association rather than direction, both CHST12-to-partner and partner-to-CHST12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, UNC45B grouped by CHST12-low versus CHST12-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHST12→partner) and Y-score (partner→CHST12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	UNC45B →	+0.144	+4.408	<.001	.001	3	2
BLOOD_Leukemia	C20orf85 →	+0.027	+3.969	<.001	.009	3	1
BLOOD_Leukemia	SLCO1B1 →	+0.018	+3.450	<.001	.004	3	1
BLOOD_Leukemia	BTBD16 →	+0.088	+3.959	<.001	.005	3	1
BLOOD_Leukemia	PLEKHS1 →	+0.097	+3.551	<.001	.008	3	1
BLOOD_Leukemia	CST5 →	+0.335	+5.288	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 133 associations by consensus.

UNC45B by CHST12 expression — BLOOD_Leukemia

Explore this box plot interactively →