Across TCGA cell cohorts, CHRNG mutation is significantly associated with the RNA expression of many other genes, with 21 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible CHRNG-associated genes across cancer lineages are CA6, SLC38A8, and OR7D4. Each is linked with CHRNG in more than 1 cancer types. Because this analysis shows association rather than direction, both CHRNG-to-partner and partner-to-CHRNG results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHRNG→partner) and Y-score (partner→CHRNG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	CA6 →	+1.062	+3.744	<.001	.009	3	2
BLOOD_Lymphoma	SLC38A8 →	+0.069	+4.606	<.001	.001	3	1
BLOOD_Lymphoma	OR7D4 →	+0.031	+4.058	<.001	.009	3	1
BLOOD_Lymphoma	LIPF →	+0.040	+3.807	.007	.007	3	1
BLOOD_Lymphoma	GNAT3 →	+0.091	+5.584	<.001	<.001	3	1
BLOOD_Lymphoma	FAM237A →	+0.015	+4.058	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

Exploration

CHRNG survival (RNA) · tumor vs normal (RNA) · all CHRNG data types