CHRNE

Across TCGA cell cohorts, CHRNE RNA expression is significantly associated with the go_rna of many other GO terms, with 2,484 significant associations in total. OESOPHAGUS shows the largest number of these associations.

The most reproducible CHRNE-associated GO terms across cancer lineages are Regulation of myoblast fusion, Negative regulation of myoblast fusion, and Negative regulation of syncytium formation by plasma membrane fusion. Each is linked with CHRNE in more than 12 cancer types. Because this analysis shows association rather than direction, both CHRNE-to-partner and partner-to-CHRNE results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of myoblast fusion grouped by CHRNE-low versus CHRNE-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CHRNE→partner) and Y-score (partner→CHRNE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Regulation of myoblast fusion →	+0.137	+0.314	<.001	.004	3	13
OESOPHAGUS	Negative regulation of myoblast fusion →	+0.117	+0.293	<.001	<.001	3	13
STOMACH	Negative regulation of syncytium formation by plasma membrane fusion →	+0.124	+0.254	.001	<.001	3	13
OESOPHAGUS	Regulation of syncytium formation by plasma membrane fusion →	+0.125	+0.320	.001	.004	3	12
OESOPHAGUS	Regulation of proteasomal protein catabolic process →	+0.066	+0.266	<.001	.001	3	11
OESOPHAGUS	Cellular response to nutrient levels →	+0.073	+0.437	<.001	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,484 associations by consensus.

Regulation of myoblast fusion by CHRNE expression — OESOPHAGUS

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