CHRNB4

Across TCGA patient cohorts, CHRNB4 protein abundance is significantly associated with the RNA expression of many other genes, with 108 significant associations in total. COAD shows the largest number of these associations.

The most reproducible CHRNB4-associated genes across cancer lineages are SLC1A5, LRRC29, and FGFRL1. Each is linked with CHRNB4 in more than 1 cancer types. Because this analysis shows association rather than direction, both CHRNB4-to-partner and partner-to-CHRNB4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHRNB4 versus SLC1A5 in COAD, with a Pearson correlation of -0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHRNB4→partner) and Y-score (partner→CHRNB4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	SLC1A5 →	-0.567	-0.321	.007	.002	3	1
COAD	LRRC29 →	-0.294	-0.294	.003	.002	3	1
COAD	FGFRL1 →	-1.177	-0.353	.005	<.001	3	1
COAD	BCAN →	-0.630	-0.453	<.001	<.001	3	1
COAD	TSPAN31 →	-0.357	-0.259	.001	.009	3	1
COAD	FRAS1 →	-0.866	-0.337	.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 108 associations by consensus.

CHRNB4 vs SLC1A5 — COAD

Explore this scatter interactively →