CHRNA1

Across TCGA patient cohorts, CHRNA1 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,741 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible CHRNA1-associated proteins across cancer lineages are FILIP1L, RTN4, and ITGB5. Each is linked with CHRNA1 in more than 3 cancer types. Because this analysis shows association rather than direction, both CHRNA1-to-partner and partner-to-CHRNA1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHRNA1 versus FILIP1L in OV, with a Pearson correlation of 0.27.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CHRNA1→partner) and Y-score (partner→CHRNA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	FILIP1L →	+0.520	+0.698	<.001	.005	3	4
HNSC	RTN4 →	+0.357	+1.575	<.001	<.001	3	3
OV	ITGB5 →	+0.692	+0.703	<.001	.004	3	3
OV	LACC1 →	+0.827	+0.868	<.001	<.001	3	3
OV	LAS1L_S560 →	-1.019	-0.653	.001	.001	3	3
HNSC	MAP1A →	+0.414	+1.383	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,741 associations by consensus.

CHRNA1 vs FILIP1L — OV

Explore this scatter interactively →