Across TCGA cell cohorts, CHRM5 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,579 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible CHRM5-associated GO terms across cancer lineages are Microtubule polymerization, Negative regulation of DNA-templated transcription initiation, and Negative regulation of mRNA splicing, via spliceosome. Each is linked with CHRM5 in more than 10 cancer types. Because this analysis shows association rather than direction, both CHRM5-to-partner and partner-to-CHRM5 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CHRM5→partner) and Y-score (partner→CHRM5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Microtubule polymerization →	+0.094	+0.099	<.001	<.001	3	10
PANCREAS	Negative regulation of DNA-templated transcription initiation →	+0.109	+0.076	.003	.001	3	9
SOFT_TISSUE	Negative regulation of mRNA splicing, via spliceosome →	+0.103	+0.134	<.001	<.001	2	10
SOFT_TISSUE	Negative regulation of mRNA processing →	+0.102	+0.127	<.001	<.001	2	10
PANCREAS	Negative regulation of transcription initiation by RNA polymerase II →	+0.109	+0.076	.003	.001	3	9
SKIN	Positive regulation of chromosome organization →	+0.059	+0.067	.002	.006	1	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,579 associations by consensus.

Exploration

CHRM5 survival (RNA) · tumor vs normal (RNA) · all CHRM5 data types