CHRM4

Across TCGA patient cohorts, CHRM4 protein abundance is significantly associated with the protein abundance of many other proteins, with 6,914 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CHRM4-associated proteins across cancer lineages are ARPC5L_S64, ARPP21, and ARPP21_S33. Each is linked with CHRM4 in more than 1 cancer types. Because this analysis shows association rather than direction, both CHRM4-to-partner and partner-to-CHRM4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHRM4 versus ARPC5L_S64 in GBM, with a Pearson correlation of 0.71.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CHRM4→partner) and Y-score (partner→CHRM4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ARPC5L_S64 →	+0.577	+0.527	<.001	<.001	3	1
GBM	ARPP21 →	+0.601	+0.563	<.001	<.001	3	1
GBM	ARPP21_S33 →	+1.120	+0.534	<.001	<.001	3	1
GBM	ARPP21_S364 →	+0.728	+0.603	<.001	<.001	3	1
GBM	ARPP21_S383 →	+0.736	+0.643	<.001	<.001	3	1
GBM	ARRB1 →	+0.387	+0.596	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,914 associations by consensus.

CHRM4 vs ARPC5L_S64 — GBM

Explore this scatter interactively →