CHRM3-AS1

Across TCGA pan-cancer cohorts, CHRM3-AS1 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated CHRM3-AS1 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher CHRM3-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated CHRM3-AS1 expression acts as an unfavorable survival marker, although some lineages such as KIRP and LUSC show a favorable association.

MESO, CHOL, and KICH are the cancer types where CHRM3-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Tertile	All	0.250	0.564	.001	99	view →
CHOL	DFS	Tertile	III,IV	0.031	0.505	.003	54	view →
KICH	DFS	Quartile	II,III,IV	0.220	0.851	<.001	46	view →
KIRP	DFS	Median	IV	0.623	0.039	.001	41	view →
LUSC	OS	Quartile	II,III,IV	0.754	0.549	.003	36	view →
ACC	OS	Tertile	All	0.476	0.815	.005	36	view →
THCA	DFS	Tertile	IV	0.422	0.908	<.001	33	view →
READ	DFS	Tertile	IV	0.333	0.752	.002	31	view →
LUAD	DFS	Tertile	All	0.547	0.702	.005	21	view →
PRAD	DFS	Quartile	All	0.937	0.713	<.001	20	view →
UVM	DFS	Tertile	All	0.324	0.772	.014	18	view →
PAAD	OS	Tertile	II,III,IV	0.323	0.593	.003	17	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

CHRM3-AS1–MESO (OS)

Open the MESO breakdown →