CHRM2

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CHRM2 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,897 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CHRM2-associated proteins across cancer lineages are PNP, DPYD, and DPYD_S905. Each is linked with CHRM2 in more than 5 cancer types. Because this analysis shows association rather than direction, both CHRM2-to-partner and partner-to-CHRM2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHRM2 versus PNP in UCEC, with a Pearson correlation of -0.27.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CHRM2→partner) and Y-score (partner→CHRM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECPNP →-0.392-0.821<.001.00136
GBMDPYD →-0.836-0.373<.001<.00134
GBMDPYD_S905 →-0.738-0.392<.001<.00134
COADGAP43 →+0.939+0.764<.001<.00134
COADPTMS →+0.636+0.655<.001<.00134
UCECPTN →+0.867+0.924<.001.00234
Each partner links to its Q-omics profile. Showing the 6 strongest of 17,897 associations by consensus.

CHRM2 vs PNP — UCEC

Per-sample scatter of CHRM2 vs PNP in UCEC (Pearson r = -0.27).

Explore this scatter interactively →

Exploration