CHRM2

Across TCGA cell cohorts, CHRM2 RNA expression is significantly associated with the go_rna of many other GO terms, with 659 significant associations in total. CNS shows the largest number of these associations.

The most reproducible CHRM2-associated GO terms across cancer lineages are Negative regulation of fatty acid transport, Primary miRNA processing, and T cell homeostasis. Each is linked with CHRM2 in more than 3 cancer types. Because this analysis shows association rather than direction, both CHRM2-to-partner and partner-to-CHRM2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of fatty acid transport grouped by CHRM2-low versus CHRM2-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CHRM2→partner) and Y-score (partner→CHRM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Negative regulation of fatty acid transport →	+0.181	+0.058	<.001	<.001	3	4
LUNG_NSCLC_LUAD	Primary miRNA processing →	+0.046	+0.042	.007	.003	3	4
LUNG_NSCLC_LUAD	T cell homeostasis →	+0.066	+0.027	.001	.008	3	4
BONE	T-helper 17 type immune response →	+0.119	+1.479	.008	.004	3	4
CNS	Platelet-derived growth factor receptor signaling pathway →	+0.049	+0.485	.007	.002	3	4
CNS	Neural nucleus development →	+0.066	+0.644	.001	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 659 associations by consensus.

Negative regulation of fatty acid transport by CHRM2 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →