CHRFAM7A

Across TCGA patient cohorts, CHRFAM7A RNA expression is significantly associated with the go_rna of many other GO terms, with 7,155 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CHRFAM7A-associated GO terms across cancer lineages are Post-Golgi vesicle-mediated transport, Golgi vesicle transport, and Positive regulation of canonical Wnt signaling pathway. Each is linked with CHRFAM7A in more than 28 cancer types. Because this analysis shows association rather than direction, both CHRFAM7A-to-partner and partner-to-CHRFAM7A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Post-Golgi vesicle-mediated transport grouped by CHRFAM7A-low versus CHRFAM7A-high in SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CHRFAM7A→partner) and Y-score (partner→CHRFAM7A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	Post-Golgi vesicle-mediated transport →	+0.063	+0.643	<.001	<.001	3	29
SCLC	Golgi vesicle transport →	+0.079	+0.877	<.001	<.001	3	28
DLBC	Positive regulation of canonical Wnt signaling pathway →	+0.050	+0.128	.007	<.001	2	28
STAD	Obsolete selective autophagy →	+0.051	+0.148	<.001	<.001	3	27
STAD	Translational elongation →	+0.049	+0.105	<.001	.001	3	27
SCLC	Cytosolic transport →	+0.076	+0.709	<.001	<.001	2	27

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,155 associations by consensus.

Post-Golgi vesicle-mediated transport by CHRFAM7A expression — SCLC

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