CHRFAM7A

Across TCGA cell cohorts, CHRFAM7A RNA expression is significantly associated with the go_rna of many other GO terms, with 3,846 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CHRFAM7A-associated GO terms across cancer lineages are Cytoplasmic translation, Nucleoside triphosphate biosynthetic process, and Positive regulation of DNA metabolic process. Each is linked with CHRFAM7A in more than 10 cancer types. Because this analysis shows association rather than direction, both CHRFAM7A-to-partner and partner-to-CHRFAM7A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytoplasmic translation grouped by CHRFAM7A-low versus CHRFAM7A-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CHRFAM7A→partner) and Y-score (partner→CHRFAM7A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Cytoplasmic translation →	+0.085	+0.645	<.001	<.001	3	11
LUNG_SCLC	Nucleoside triphosphate biosynthetic process →	+0.079	+1.214	<.001	<.001	3	11
LARGE_INTESTINE	Positive regulation of DNA metabolic process →	+0.042	+0.556	<.001	<.001	3	10
BREAST	Negative regulation of myoblast fusion →	+0.103	+0.586	<.001	.002	3	10
KIDNEY	Negative regulation of syncytium formation by plasma membrane fusion →	+0.101	+1.020	<.001	.001	3	10
BLOOD_Lymphoma	Positive regulation of translation →	+0.048	+0.312	<.001	.006	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,846 associations by consensus.

Cytoplasmic translation by CHRFAM7A expression — BREAST

Explore this box plot interactively →