CHRFAM7A

Across TCGA cell cohorts, CHRFAM7A mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CHRFAM7A-associated genes across cancer lineages are C1QTNF7, ACER1, and CT45A8. Each is linked with CHRFAM7A in more than 1 cancer types. Because this analysis shows association rather than direction, both CHRFAM7A-to-partner and partner-to-CHRFAM7A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C1QTNF7 grouped by CHRFAM7A-low versus CHRFAM7A-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHRFAM7A→partner) and Y-score (partner→CHRFAM7A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	C1QTNF7 →	+0.098	+4.108	<.001	.008	3	1
LARGE_INTESTINE	ACER1 →	+0.120	+3.823	<.001	.006	3	1
LARGE_INTESTINE	CT45A8 →	+0.024	+3.793	.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

C1QTNF7 by CHRFAM7A expression — LARGE_INTESTINE

Explore this box plot interactively →