CHRDL2

Across TCGA cell cohorts, CHRDL2 RNA expression is significantly associated with the go_rna of many other GO terms, with 494 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CHRDL2-associated GO terms across cancer lineages are Regulation of T cell migration, Protein localization to postsynaptic membrane, and Negative regulation of skeletal muscle cell proliferation. Each is linked with CHRDL2 in more than 4 cancer types. Because this analysis shows association rather than direction, both CHRDL2-to-partner and partner-to-CHRDL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of T cell migration grouped by CHRDL2-low versus CHRDL2-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CHRDL2→partner) and Y-score (partner→CHRDL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Regulation of T cell migration →	-0.071	-0.025	<.001	.001	3	5
LUNG_NSCLC_LUAD	Protein localization to postsynaptic membrane →	-0.073	-0.452	.003	.007	2	5
SOFT_TISSUE	Negative regulation of skeletal muscle cell proliferation →	+0.192	+0.266	<.001	.002	3	3
SOFT_TISSUE	Negative regulation of skeletal muscle satellite cell proliferation →	+0.192	+0.266	<.001	.002	3	3
SOFT_TISSUE	Negative regulation of TORC1 signaling →	+0.040	+0.166	<.001	.001	2	4
LIVER	Ganglioside catabolic process →	+0.236	+2.150	<.001	.008	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 494 associations by consensus.

Regulation of T cell migration by CHRDL2 expression — BLOOD_Leukemia

Explore this box plot interactively →