CHRAC1

Across TCGA patient cohorts, CHRAC1 protein abundance is significantly associated with the RNA expression of many other genes, with 14,541 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CHRAC1-associated genes across cancer lineages are VRK1, SMC2, and DNA2. Each is linked with CHRAC1 in more than 7 cancer types. Because this analysis shows association rather than direction, both CHRAC1-to-partner and partner-to-CHRAC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHRAC1 versus VRK1 in LSCC, with a Pearson correlation of 0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHRAC1→partner) and Y-score (partner→CHRAC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	VRK1 →	+0.830	+0.334	<.001	<.001	3	8
LSCC	SMC2 →	+0.898	+0.358	<.001	<.001	3	8
LSCC	DNA2 →	+0.773	+0.344	<.001	<.001	3	8
LSCC	PRIM2 →	+0.742	+0.430	<.001	<.001	3	8
LSCC	ATAD2 →	+1.049	+0.490	<.001	<.001	3	8
OV	RACGAP1 →	+1.035	+0.802	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,541 associations by consensus.

CHRAC1 vs VRK1 — LSCC

Explore this scatter interactively →