CHPT1

Across TCGA pan-cancer cohorts, CHPT1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated CHPT1 data layer compared with 24 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher CHPT1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated CHPT1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and PDAC show a favorable association.

CCRCC, HNSC, and PDAC are the cancer types where CHPT1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Median	III,IV	0.105	0.904	.008	9	view →
HNSC	DFS	Median	All	0.936	0.659	.027	5	view →
PDAC	OS	Quartile	All	0.951	0.548	.031	4	view →
GBM	DFS	Median	All	0.633	0.778	.022	2	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

CHPT1–CCRCC (DFS)

Open the CCRCC breakdown →