CHPT1

Across TCGA patient cohorts, CHPT1 protein abundance is significantly associated with the RNA expression of many other genes, with 5,257 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CHPT1-associated genes across cancer lineages are SYCP3, ADGRF1, and SLC30A2. Each is linked with CHPT1 in more than 2 cancer types. Because this analysis shows association rather than direction, both CHPT1-to-partner and partner-to-CHPT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHPT1 versus SYCP3 in LUAD, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHPT1→partner) and Y-score (partner→CHPT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	SYCP3 →	+0.533	+0.472	<.001	<.001	3	3
LUAD	ADGRF1 →	-1.748	-0.452	.002	<.001	3	2
OV	SLC30A2 →	+1.914	+1.505	.005	.002	3	2
HNSC	RNU6-1189P →	-1.348	-1.331	.002	.003	3	2
HNSC	ZSCAN5DP →	+0.471	+0.927	.003	.004	3	2
CCRCC	SORD →	+0.691	+0.322	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,257 associations by consensus.

CHPT1 vs SYCP3 — LUAD

Explore this scatter interactively →