CHPF2

Across TCGA patient cohorts, CHPF2 protein abundance is significantly associated with the RNA expression of many other genes, with 12,820 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CHPF2-associated genes across cancer lineages are PDIA4, PLOD1, and TSHZ1. Each is linked with CHPF2 in more than 4 cancer types. Because this analysis shows association rather than direction, both CHPF2-to-partner and partner-to-CHPF2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHPF2 versus PDIA4 in OV, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHPF2→partner) and Y-score (partner→CHPF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PDIA4 →	+0.669	+0.357	<.001	.004	3	5
LSCC	PLOD1 →	+0.736	+0.278	<.001	<.001	3	5
GBM	TSHZ1 →	-0.640	-0.395	<.001	<.001	3	5
GBM	CALU →	+0.630	+0.461	<.001	<.001	3	5
OV	CD276 →	+0.914	+0.395	<.001	.001	3	4
HNSC	CHSY1 →	+0.630	+0.269	<.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,820 associations by consensus.

CHPF2 vs PDIA4 — OV

Explore this scatter interactively →