CHPF2

Across TCGA cell cohorts, CHPF2 mutation is significantly associated with the RNA expression of many other genes, with 719 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CHPF2-associated genes across cancer lineages are GPR101, OR10A5, and OR8B12. Each is linked with CHPF2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CHPF2-to-partner and partner-to-CHPF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GPR101 grouped by CHPF2-low versus CHPF2-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHPF2→partner) and Y-score (partner→CHPF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	GPR101 →	+0.019	+3.990	<.001	.003	3	1
OVARY	OR10A5 →	+0.041	+4.444	<.001	.001	3	1
OVARY	OR8B12 →	+0.014	+4.222	<.001	.006	3	1
OVARY	OR1L6 →	+0.012	+4.222	<.001	.006	3	1
OVARY	GPR148 →	+0.054	+4.095	<.001	.003	3	1
OVARY	TPPP2 →	+0.091	+3.657	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 719 associations by consensus.

GPR101 by CHPF2 expression — OVARY

Explore this box plot interactively →