CHPF

Across TCGA pan-cancer cohorts, CHPF RNA differs between tumor and matched normal tissue in 17 of 18 cancer types tested, making tumor–normal expression one of CHPF’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where CHPF RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CHPF is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

HNSC, COAD, and KIRP are the cancer types where CHPF tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CHPF RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Female	IV	+2.045	<.001	12	view →
COAD	Male	III,IV	+2.202	<.001	11	view →
KIRP	All	III,IV	+1.569	<.001	11	view →
KIRC	Female	All	+0.957	<.001	11	view →
LUAD	Female	III,IV	+2.072	<.001	9	view →
LUSC	All	III,IV	+1.549	<.001	8	view →
BRCA	All	III,IV	+1.524	<.001	8	view →
READ	All	II,III,IV	+2.000	<.001	7	view →
STAD	Male	II,III,IV	+1.781	<.001	7	view →
KICH	Male	All	−1.139	<.001	7	view →
BLCA	All	All	+0.868	<.001	7	view →
LIHC	Female	All	+1.042	<.001	6	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 17 lineages.

CHPF–HNSC

Open the HNSC breakdown →