CHODL

Across TCGA cell cohorts, CHODL RNA expression is significantly associated with the go_rna of many other GO terms, with 1,642 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible CHODL-associated GO terms across cancer lineages are Regulation of cytoplasmic translation, Negative regulation of RNA catabolic process, and RNA stabilization. Each is linked with CHODL in more than 5 cancer types. Because this analysis shows association rather than direction, both CHODL-to-partner and partner-to-CHODL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of cytoplasmic translation grouped by CHODL-low versus CHODL-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CHODL→partner) and Y-score (partner→CHODL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Regulation of cytoplasmic translation →	+0.121	+1.437	<.001	.002	3	6
KIDNEY	Negative regulation of RNA catabolic process →	+0.067	+0.350	<.001	.005	3	6
KIDNEY	RNA stabilization →	+0.054	+0.277	<.001	.001	3	6
OVARY	Purine nucleoside triphosphate biosynthetic process →	+0.101	+1.278	<.001	.001	3	5
OVARY	Purine ribonucleotide biosynthetic process →	+0.074	+1.031	<.001	.007	3	5
OVARY	Purine ribonucleoside triphosphate biosynthetic process →	+0.101	+1.278	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,642 associations by consensus.

Regulation of cytoplasmic translation by CHODL expression — OESOPHAGUS

Explore this box plot interactively →