CHODL-AS1

Across TCGA pan-cancer cohorts, CHODL-AS1 RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated CHODL-AS1 data layer.

The strongest signal is observed in rectum adenocarcinoma (READ), where higher CHODL-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated CHODL-AS1 expression acts as an unfavorable survival marker, although some lineages such as LUSC and BLCA show a favorable association.

READ, DLBC, and LUSC are the cancer types where CHODL-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
READ	DFS	Tertile	III,IV	0.286	0.781	<.001	102	view →
DLBC	OS	Quartile	All	0.414	0.822	.005	49	view →
LUSC	DFS	Median	II,III,IV	0.462	0.284	.007	38	view →
UCEC	DFS	Tertile	All	0.827	0.909	.001	24	view →
PCPG	OS	Tertile	All	0.816	0.981	.018	18	view →
COAD	OS	Tertile	IV	0.211	0.655	.034	18	view →
LUAD	DFS	Quartile	III,IV	0.432	0.685	.012	14	view →
UVM	OS	Tertile	All	0.397	0.734	.046	12	view →
KIRP	OS	Tertile	All	0.309	0.718	.007	12	view →
BLCA	OS	Tertile	All	0.567	0.282	.031	6	view →
PAAD	DFS	Tertile	II,III,IV	0.480	0.232	.046	6	view →
PRAD	OS	Tertile	All	0.715	0.891	.005	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

CHODL-AS1–READ (DFS)

Open the READ breakdown →