CHN1

Across TCGA pan-cancer cohorts, CHN1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated CHN1 data layer compared with 23 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher CHN1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated CHN1 expression acts as an unfavorable survival marker, although some lineages such as PDAC and LUAD show a favorable association.

PDAC, LUAD, and UCEC are the cancer types where CHN1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Median	All	0.473	0.235	.008	16	view →
LUAD	DFS	Tertile	All	1.000	0.436	.003	12	view →
UCEC	OS	Median	All	0.912	0.989	.046	4	view →
HNSC	OS	Median	All	0.947	1.000	.019	2	view →
LSCC	OS	Median	III,IV	0.841	0.467	.025	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

CHN1–PDAC (DFS)

Open the PDAC breakdown →