CHMP7

Across TCGA patient cohorts, CHMP7 RNA expression is significantly associated with the mutation status of many other genes, with 11,335 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CHMP7-associated genes across cancer lineages are TP53, PIK3CA, and NAV3. Each is linked with CHMP7 in more than 5 cancer types. Because this analysis shows association rather than direction, both CHMP7-to-partner and partner-to-CHMP7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TP53 grouped by CHMP7-low versus CHMP7-high in LUAD.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHMP7→partner) and Y-score (partner→CHMP7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	TP53 →	-0.928	-0.194	<.001	<.001	3	6
STAD	PIK3CA →	+2.338	+0.405	<.001	<.001	3	5
UCEC	NAV3 →	+1.925	+0.382	<.001	<.001	3	5
COAD	DOCK2 →	+2.210	+0.445	<.001	<.001	3	4
COAD	TACC2 →	+2.595	+0.392	.006	.002	3	4
COAD	BRD4 →	+2.847	+0.452	.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,335 associations by consensus.

TP53 by CHMP7 expression — LUAD

Explore this box plot interactively →