CHMP7

Across TCGA patient cohorts, CHMP7 protein abundance is significantly associated with the RNA expression of many other genes, with 4,062 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CHMP7-associated genes across cancer lineages are TNFRSF10A, PPP2R2A, and XPO7. Each is linked with CHMP7 in more than 7 cancer types. Because this analysis shows association rather than direction, both CHMP7-to-partner and partner-to-CHMP7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHMP7 versus TNFRSF10A in OV, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHMP7→partner) and Y-score (partner→CHMP7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	TNFRSF10A →	+1.060	+0.325	<.001	.002	3	8
BRCA	PPP2R2A →	+0.730	+0.329	<.001	<.001	3	8
OV	XPO7 →	+0.835	+0.370	<.001	<.001	3	7
OV	INTS10 →	+0.535	+0.300	<.001	<.001	3	6
OV	VPS37A →	+0.669	+0.334	<.001	<.001	3	6
OV	POLR3D →	+0.812	+0.363	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,062 associations by consensus.

CHMP7 vs TNFRSF10A — OV

Explore this scatter interactively →