CHMP4A

Across TCGA patient cohorts, CHMP4A RNA expression is significantly associated with the protein abundance of many other proteins, with 10,940 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CHMP4A-associated proteins across cancer lineages are APEX1, SUPT16H, and SSRP1. Each is linked with CHMP4A in more than 5 cancer types. Because this analysis shows association rather than direction, both CHMP4A-to-partner and partner-to-CHMP4A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHMP4A versus APEX1 in GBM, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CHMP4A→partner) and Y-score (partner→CHMP4A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	APEX1 →	+0.465	+0.460	<.001	<.001	3	6
GBM	SUPT16H →	+0.521	+0.342	<.001	<.001	3	6
GBM	SSRP1 →	+0.581	+0.438	<.001	<.001	3	5
OV	STRN3 →	+0.215	+0.487	.002	.003	3	5
LSCC	GFPT1 →	-0.341	-0.345	<.001	.001	3	4
GBM	RALGAPA1 →	+0.226	+0.262	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,940 associations by consensus.

CHMP4A vs APEX1 — GBM

Explore this scatter interactively →