CHMP3

Across TCGA patient cohorts, CHMP3 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,531 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CHMP3-associated proteins across cancer lineages are ARHGAP30, SAMSN1, and EPS15_S221. Each is linked with CHMP3 in more than 6 cancer types. Because this analysis shows association rather than direction, both CHMP3-to-partner and partner-to-CHMP3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHMP3 versus ARHGAP30 in GBM, with a Pearson correlation of -0.27.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CHMP3→partner) and Y-score (partner→CHMP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ARHGAP30 →	-0.456	-0.188	.003	.003	3	7
LSCC	SAMSN1 →	-0.594	-0.531	<.001	<.001	3	6
GBM	EPS15_S221 →	-0.506	-0.308	<.001	<.001	3	6
LSCC	LSP1_S252 →	-0.669	-0.518	<.001	<.001	3	6
LSCC	ARHGEF6_S225 →	-0.795	-0.480	<.001	<.001	3	6
GBM	DOK3 →	-0.463	-0.207	.004	.008	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,531 associations by consensus.

CHMP3 vs ARHGAP30 — GBM

Explore this scatter interactively →