CHMP3

Across TCGA patient cohorts, CHMP3 protein abundance is significantly associated with the RNA expression of many other genes, with 9,166 significant associations in total. OV shows the largest number of these associations.

The most reproducible CHMP3-associated genes across cancer lineages are HS1BP3, AFTPH, and SEPTIN10. Each is linked with CHMP3 in more than 4 cancer types. Because this analysis shows association rather than direction, both CHMP3-to-partner and partner-to-CHMP3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CHMP3 versus HS1BP3 in LSCC, with a Pearson correlation of 0.31.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CHMP3→partner) and Y-score (partner→CHMP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	HS1BP3 →	+0.476	+0.305	<.001	.005	3	5
OV	AFTPH →	+0.484	+0.292	<.001	.006	3	4
LSCC	SEPTIN10 →	+0.656	+0.328	.001	.005	3	4
UCEC	AHNAK →	+0.556	+0.216	.004	.009	3	3
LSCC	NECTIN4 →	+1.025	+0.340	.001	.001	3	3
HNSC	GIPC1 →	+0.917	+0.257	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,166 associations by consensus.

CHMP3 vs HS1BP3 — LSCC

Explore this scatter interactively →